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从意大利睡鼠(Myoxus glis)中分离出脑心肌炎病毒。

Isolation of encephalomyocarditis virus from dormice (Myoxus glis) in Italy.

作者信息

Amaddeo D, Cardeti G, Autorino G L

机构信息

Virology Laboratory, Istituto Zooprofilattico Sperimentale delle Regioni Lazio e Toscana, Roma, Italy.

出版信息

J Wildl Dis. 1995 Apr;31(2):238-42. doi: 10.7589/0090-3558-31.2.238.

Abstract

Two isolates of encephalomyocarditis (EMC) virus (ZRC 276RA/90 and ZRC 292RA/90) were isolated from two dormice (Myoxus glis) in Tuscany, Italy. The two isolates were lethal for laboratory mice and caused a rapid cytopathic effect characterized by rounded and wrinkled cells in both baby hamster kidney cells (BHK21) and African green monkey kidney cells (Vero). We found neutralizing antibodies against EMC virus in 408 (77%) of 529 domestic pigs (Sus scrofa scrofa) and in 165 (49%) of 338 wild boars (S. scrofa ferus majori) in Tuscany.

摘要

从意大利托斯卡纳的两只睡鼠(Myoxus glis)中分离出两株脑心肌炎(EMC)病毒(ZRC 276RA/90和ZRC 292RA/90)。这两株病毒对实验小鼠具有致死性,并在幼仓鼠肾细胞(BHK21)和非洲绿猴肾细胞(Vero)中引起快速细胞病变效应,其特征为细胞变圆和起皱。我们在托斯卡纳的529头家猪(Sus scrofa scrofa)中的408头(77%)以及338头野猪(S. scrofa ferus majori)中的165头(49%)体内发现了针对EMC病毒的中和抗体。

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