Knowles N J, Dickinson N D, Wilsden G, Carra E, Brocchi E, De Simone F
Institute for Animal Health, Pirbright Laboratory, Surrey, UK.
Virus Res. 1998 Sep;57(1):53-62. doi: 10.1016/s0168-1702(98)00081-1.
Partial nucleotide sequences of encephalomyocarditis (EMC) viruses isolated from five, apparently independent, outbreaks of fatal myocarditis in pigs in Italy were compared with three EMC viruses isolated from wild rodents from a different geographic region in the same country. These viruses were also compared with EMC viruses isolated from pigs in other European countries and three historical strains. All the Italian EMC viruses were closely related (> 94.6% nucleotide identity), but were distinct from viruses occurring in Belgium in 1991 (< 80.5% nucleotide identity), Greece in 1990 (< 83.3% nucleotide identity) and the three older viruses (< 82.9% nucleotide identity). An EMC virus isolated from pigs in the Netherlands in 1988, was closely related to the Italian viruses (95.3-99.3% nucleotide identity). It is suggested that pigs may play a role in the movement of EMC viruses between different geographic regions.
将从意大利五起明显独立的猪致命心肌炎疫情中分离出的脑心肌炎（EMC）病毒的部分核苷酸序列，与从同一国家不同地理区域的野生啮齿动物中分离出的三种EMC病毒进行了比较。还将这些病毒与从其他欧洲国家的猪中分离出的EMC病毒以及三种历史毒株进行了比较。所有意大利的EMC病毒都密切相关（核苷酸同一性>94.6%），但与1991年在比利时出现的病毒（核苷酸同一性<80.5%）、1990年在希腊出现的病毒（核苷酸同一性<83.3%）以及三种较老的病毒（核苷酸同一性<82.9%）不同。1988年从荷兰猪中分离出的一种EMC病毒与意大利病毒密切相关（核苷酸同一性为95.3 - 99.3%）。有人认为猪可能在EMC病毒在不同地理区域之间的传播中起作用。
