Hasslacher C, Thamer G, Wahl P, Kommerell B
Diabete Metab. 1977 Mar;3(1):19-21.
The frequency of antibodies to the hepatitis B surface antigen was determined in 406 diabetics in two study series separated in time (1971-1972 and 1974-1975). In the 1971-1972 series, the antibody frequency in insulin and orally treated patients was significantly higher, and the incidence of hepatitis was also greater. The decline in the antibody frequency in the 1974-1975 series is primarily attributed to improved hygienic measures. Anti-HBs was more frequently demonstrable in insulin-dependent diabetics than in orally treated patients. Since the duration of diabetes was about three times as long in this treatment group and the frequency of metabolic checks twice as great, the raised antibody frequency in insulin-injecting diabetics was attributed to greater exposure to the virus.
在两个时间上分开的研究系列（1971 - 1972年和1974 - 1975年）中，对406名糖尿病患者进行了乙型肝炎表面抗原抗体频率的测定。在1971 - 1972年的系列中，胰岛素治疗和口服药物治疗的患者抗体频率显著更高，肝炎发病率也更高。1974 - 1975年系列中抗体频率的下降主要归因于卫生措施的改善。胰岛素依赖型糖尿病患者中抗 - HBs比口服药物治疗的患者更常被检测到。由于该治疗组糖尿病病程约为口服药物治疗组的三倍，代谢检查频率为口服药物治疗组的两倍，注射胰岛素的糖尿病患者抗体频率升高归因于病毒暴露更多。
