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[超快速计算机断层扫描在冠心病诊断中的应用]

[Use of ultra-fast computerized tomography in diagnosis of coronary heart disease].

作者信息

von Smekal A, Knez A, Seelos K C, Pittermann I, Haberl R, Stehling M K, Steinbeck G, Reiser M

机构信息

Institut für Radiologische Diagnostik, Universität München.

出版信息

Radiologe. 1995 Dec;35(12):984-90.

PMID:8584643
Abstract

Ultrafast or electron beam tomography (EBT) permits acquisition of images in 50-100 ms. An artifact-reduced display of heart and vessel structures as well as calcifications can be achieved. Therefore, EBT can be used for the detection and quantification of coronary artery calcification. Thirty-two patients with known coronary artery disease (CAD) were studied by EBT with and without i.v. contrast enhancement and with conventional coronary angiography. Different scoring systems were applied in order to define the basis to compare the data. The results showed a high EBT sensitivity for detection of coronary artery stenosis of up to 94% but low specificity with a maximum of 75%, depending on the scoring system applied. With EBT, differentiation between significant CAD (> 75%) and low-grade CAD (0-75%) showed significant results. The scoring system is not yet completely satisfactory, and with the integration of other screening tests and continuous development of scoring systems, the significance and reliability of this method in evaluation of CAD are expected to increase.

摘要

超速或电子束断层扫描(EBT)能够在50 - 100毫秒内采集图像。可以实现心脏和血管结构以及钙化的减少伪影的显示。因此,EBT可用于冠状动脉钙化的检测和定量。32例已知冠心病(CAD)患者接受了EBT检查,分别采用静脉注射造影剂增强和不增强的方式,并进行了传统冠状动脉造影。应用了不同的评分系统以便为比较数据奠定基础。结果显示,根据所应用的评分系统,EBT检测冠状动脉狭窄的敏感性高达94%,但特异性较低,最高为75%。通过EBT,重度CAD(> 75%)和轻度CAD(0 - 75%)之间的区分显示出显著结果。评分系统尚未完全令人满意,随着其他筛查试验的整合以及评分系统的不断发展,预计该方法在评估CAD中的重要性和可靠性将会提高。

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