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双(2-羟乙基硫代)-1,10-癸二醇在高脂血症治疗中的应用(作者译)

[Bis-(hydroxy-2-ethylthyo)-1,10-decano in hyperlipaemic therapy (author's transl)].

作者信息

Cucinotta D, Palummeri E, Ceccato S, Passeri M

出版信息

G Ital Cardiol. 1977;7(3):248-64.

PMID:858465
Abstract

The authors studied the effectiveness and biological tolerability of Tiadenol [Bis-(hydroxy-2-ethylthyo)-1,10-decano] against clofibrate, in a group of 38 hyperlipaemic (volunteers) subjects, with or without atherosclerotic disease. The results showed that the new hypolipidaemic drug has a great effect on cholesterolemia and trigliceridaemia, as does clofibrate. The statistic examination confirmed the results. This research didn't show any side-effects of the drug, which has a very good biological tolerability.

摘要

作者在一组38名患有或未患有动脉粥样硬化疾病的高脂血症(志愿者)受试者中,研究了替阿地诺[双-(羟基-2-乙基硫代)-1,10-癸烷]相对于氯贝丁酯的有效性和生物耐受性。结果显示,这种新型降血脂药物对胆固醇血症和甘油三酯血症有显著效果,氯贝丁酯也是如此。统计学检验证实了这些结果。该研究未显示出该药物有任何副作用,其具有非常好的生物耐受性。

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1
[Bis-(hydroxy-2-ethylthyo)-1,10-decano in hyperlipaemic therapy (author's transl)].双(2-羟乙基硫代)-1,10-癸二醇在高脂血症治疗中的应用(作者译)
G Ital Cardiol. 1977;7(3):248-64.
2
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3
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Clinical research into the hypolipemic and platelet antiaggregant activity of plafibride, Carried out in double-blind conditions and in comparison with clofibrate.在双盲条件下进行的普拉贝特降血脂和抗血小板聚集活性的临床研究,并与氯贝丁酯作比较。
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[The clinical use of bis-(hydroxy-ethyl-thio)-1,10-decane in the treatment of hyperlipemic and dyslipemic conditions].双(羟乙基硫代)-1,10-癸烷在高脂血症和血脂异常病症治疗中的临床应用
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