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双(2-羟乙基硫代)-1,10-癸二醇在高脂血症治疗中的应用(作者译)

[Bis-(hydroxy-2-ethylthyo)-1,10-decano in hyperlipaemic therapy (author's transl)].

作者信息

Cucinotta D, Palummeri E, Ceccato S, Passeri M

出版信息

G Ital Cardiol. 1977;7(3):248-64.

PMID:858465
Abstract

The authors studied the effectiveness and biological tolerability of Tiadenol [Bis-(hydroxy-2-ethylthyo)-1,10-decano] against clofibrate, in a group of 38 hyperlipaemic (volunteers) subjects, with or without atherosclerotic disease. The results showed that the new hypolipidaemic drug has a great effect on cholesterolemia and trigliceridaemia, as does clofibrate. The statistic examination confirmed the results. This research didn't show any side-effects of the drug, which has a very good biological tolerability.

摘要

作者在一组38名患有或未患有动脉粥样硬化疾病的高脂血症(志愿者)受试者中,研究了替阿地诺[双-(羟基-2-乙基硫代)-1,10-癸烷]相对于氯贝丁酯的有效性和生物耐受性。结果显示,这种新型降血脂药物对胆固醇血症和甘油三酯血症有显著效果,氯贝丁酯也是如此。统计学检验证实了这些结果。该研究未显示出该药物有任何副作用,其具有非常好的生物耐受性。

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