Fischer A
I. Medizinischen Tierklinik, Ludwig-Maximilians-Universität München.
Tierarztl Prax. 1995 Dec;23(6):596-602.
For differential diagnosis, therapy, and prognosis of seizures in dogs it is recommended to distinguish between two groups of diseases: 1. Epilepsy is diagnosed if seizures occur repeatedly without an active, underlying disorder. Idiopathic epilepsy occurs most commonly. A hereditary component has been demonstrated in several breeds. Symptomatic epilepsy results from previous resolved forebrain disorders, which cause epileptic seizures through scar formation. 2. Seizures are caused by active structural forebrain disease or metabolic-toxic imbalances. Upon initial presentation of the dog, a preliminary classification may be achieved with the seizure history, clinical and neurological examination, and routine laboratory evaluation. The diagnosis of idiopathic epilepsy is based on typical seizure history and exclusion of structural forebrain disease and metabolic-toxic imbalances with special laboratory testing, CSF examination, and brain scanning procedures.
对于犬癫痫发作的鉴别诊断、治疗及预后,建议区分两组疾病:1. 如果癫痫发作反复出现且无活动性潜在疾病,则诊断为癫痫。特发性癫痫最为常见。在几个品种中已证实有遗传因素。症状性癫痫由先前已缓解的前脑疾病引起,这些疾病通过瘢痕形成导致癫痫发作。2. 癫痫发作由活动性前脑结构疾病或代谢 - 毒性失衡引起。在犬初次就诊时,通过癫痫发作病史、临床和神经学检查以及常规实验室评估可进行初步分类。特发性癫痫的诊断基于典型的癫痫发作病史,并通过特殊实验室检查、脑脊液检查和脑部扫描程序排除前脑结构疾病和代谢 - 毒性失衡。