Mönig S P, Türler A, Raab M
Klinik und Poliklinik für Chirurgie, Universität zu Köln.
Zentralbl Chir. 1995;120(12):963-8.
In a retrospective study the role of thymectomy in the treatment of myasthenia gravis (n = 19) and of thymoma (n = 7) was analysed in 26 patients operated on between 1989 and 1994 in the Department of Surgery at the University of Cologne. The mean follow-up period was 28 months (follow-up rate: 96.2%). A transsternal incision was preferred in 24 cases (92.3%). Patients with myasthenia gravis were preoperatively classified according to Ossermann. Patients with thymoma were classified according to Masaoka. 17 patients (89.5%) with myasthenia gravis demonstrated a significant improvement. 4 patients (57.1%) with thymoma were free of recurrence. Stage II to IV thymoma should receive postoperative radiotherapy. Patients with stage IV lesions are usually offered postoperative radiation therapy plus cis-platinum based chemotherapy.
在一项回顾性研究中，分析了1989年至1994年间在科隆大学外科接受手术的26例患者中行胸腺切除术治疗重症肌无力（n = 19）和胸腺瘤（n = 7）的作用。平均随访期为28个月（随访率：96.2%）。24例（92.3%）患者首选经胸骨切口。重症肌无力患者术前根据奥斯默曼分类。胸腺瘤患者根据正冈分类。17例（89.5%）重症肌无力患者有显著改善。4例（57.1%）胸腺瘤患者无复发。II期至IV期胸腺瘤患者应接受术后放疗。IV期病变患者通常接受术后放疗加顺铂化疗。
