Inderbitzi R, Rösler K, Nachbur B
Universitätskliniken für Thorax-Herz- und Gefässchirurgie, Inselspital Bern.
Chirurg. 1991 Jun;62(6):474-8.
Between 1986 and 1989 27 patients with myasthenia gravis underwent radical thymectomy: 24 patients without and two patients with thymoma through a trans-sternal incision, another with thymomatous myasthenia through a left-sided thoracotomy. The patients were staged according to the modified Ossermann classification. The results were evaluated prospectively according to the Disability Status Scale of Oosterhuis. During a mean follow up of 22.4 months, 21 patients (77%) benefited from the operation with complete remission achieved in 9 (33%) and significant improvement noted in 12 (44%). There were no operative deaths and no hospital morbidity. The mean operation time was 88 minutes, the mean postoperative hospital stay 10.5 days. These results support the recommendation for radical trans-sternal thymectomy in the treatment of patients with myasthenia gravis as a safe procedure.
1986年至1989年间，27例重症肌无力患者接受了根治性胸腺切除术：24例无胸腺瘤患者和2例胸腺瘤患者经胸骨正中切口手术，另1例胸腺瘤性重症肌无力患者经左侧开胸手术。患者根据改良的奥斯勒曼分类法进行分期。根据奥斯特huis残疾状态量表对结果进行前瞻性评估。在平均22.4个月的随访期间，21例患者（77%）从手术中获益，9例（33%）实现完全缓解，12例（44%）有显著改善。无手术死亡病例，也无医院内并发症。平均手术时间为88分钟，术后平均住院时间为10.5天。这些结果支持将根治性胸骨正中胸腺切除术作为治疗重症肌无力患者的一种安全手术的建议。
