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[三叉神经病变感觉障碍的神经生理学分析]

[A neurophysiological analysis of the sensory disorders in trigeminal nerve neuropathy].

作者信息

Grachev Iu V, Reshetniak V K, Meĭzerov E E

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 1995;95(5):9-13.

PMID:8585388
Abstract

52 patients with various types of trigeminal nerve neuropathy were examined in terms of trigeminal somatosensory evoked potentials (TSEP). The increase of latent periods and the decrease of N5-N33 amplitude components as well as disappearance of some separate components of this period were observed in patients with moderate facial pain and hypersthesia when sore side was stimulated. Meanwhile the alterations level of TSEP correlated with trigeminal hypesthesia severity. In a course of such stimulation all TSEP components disappeared in patients with severe sensory deficit and this turned out to be unfavourable prognostic sign pointing out the small perspectivity of conservative antianalgesic therapy. TSEP investigation in patients with trigeminal nerve neuropathy promoted objectivity of face and oral cavity sensory insufficiency that permitted to estimate both the alteration degree and algesic syndrome severity.

摘要

对52例不同类型三叉神经神经病变患者进行了三叉神经体感诱发电位(TSEP)检查。当刺激患侧时,中度面部疼痛和感觉过敏患者出现潜伏期延长、N5-N33波幅成分降低以及该时段某些单独成分消失。同时,TSEP的改变程度与三叉神经感觉减退的严重程度相关。在这种刺激过程中,严重感觉障碍患者的所有TSEP成分均消失,这被证明是一个不良预后指标,表明保守镇痛治疗前景不佳。对三叉神经神经病变患者进行TSEP检查提高了面部和口腔感觉功能不全的客观性,从而能够评估改变程度和疼痛综合征的严重程度。

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