Edman K A
Department of Pharmacology, University of Lund, Sweden.
Adv Exp Med Biol. 1995;384:29-43. doi: 10.1007/978-1-4899-1016-5_3.
Two principal mechanisms underlying fatigue of isolated muscle fibers are described: failure of activation of the contractile system and reduced performance of the myofibrils due to altered kinetics of crossbridge function. The relative importance of these two mechanisms during development of fatigue is discussed.
收缩系统激活失败以及由于横桥功能动力学改变导致肌原纤维性能下降。本文讨论了这两种机制在疲劳发展过程中的相对重要性。