无名质的磁共振成像解剖及阿尔茨海默病的表现：初步报告
MR anatomy of the substantia innominata and findings in Alzheimer disease: a preliminary report.
作者信息
Sasaki M, Ehara S, Tamakawa Y, Takahashi S, Tohgi H, Sakai A, Mita T
机构信息
Center for Radiological Sciences, Iwate Medical University, Morioka, Japan.
出版信息
AJNR Am J Neuroradiol. 1995 Nov-Dec;16(10):2001-7.
PURPOSE
To demonstrate normal MR anatomy of the substantia innominata and its changes in Alzheimer disease on MR imaging.
METHODS
Using a 1.5-T superconductive MR unit, thickness of the substantia innominata was measured on coronal thin-section images obtained in 22 patients with Alzheimer disease and 14 age-matched control subjects. Comparison of these images with postmortem specimens of human brain was also performed.
RESULTS
On T2-weighted images through the anterior commissure, the substantia innominata was clearly identified between the globus pallidus and the anterior perforated substance. In Alzheimer disease, thinning of the substantia innominata was more frequently observed than in the age-matched controls.
CONCLUSION
Thin-section T2-weighted coronal MR images can demonstrate shrinkage of the substantia innominata, a finding that may aid in the diagnosis of Alzheimer disease.
目的
在磁共振成像（MR）上展示无名质的正常MR解剖结构及其在阿尔茨海默病中的变化。
方法
使用1.5-T超导MR设备，在22例阿尔茨海默病患者和14例年龄匹配的对照受试者所获得的冠状位薄层图像上测量无名质的厚度。还将这些图像与人类大脑的尸检标本进行了比较。
结果
在通过前连合的T2加权图像上，无名质在苍白球和前穿质之间清晰可见。在阿尔茨海默病中，与年龄匹配的对照相比，无名质变薄更为常见。
结论
冠状位T2加权薄层MR图像可显示无名质萎缩，这一发现可能有助于阿尔茨海默病的诊断。
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