Schvarcz E, Palmér M, Aman J, Berne C
Department of Internal Medicine, Orebro Medical Center Hospital, Sweden.
Diabetes Care. 1995 May;18(5):674-6. doi: 10.2337/diacare.18.5.674.
To compare the gastric emptying rate during normoglycemia with that during insulin-induced hypoglycemia in healthy subjects.
In eight healthy subjects, the rate of gastric emptying of an isotope-labeled meal was assessed by a scintigraphic technique during normoglycemia and hypoglycemia, both controlled by an insulin-glucose clamp.
The mean time taken to empty 50% of the test meal from the stomach (T50) for the solid phase was 43.0 +/- 20.0 min during normoglycemia, compared with 16.3 +/- 6.6 min during hypoglycemia, P < 0.001. The mean T50 for the liquid phase was 38.0 +/- 21.2 and 15.4 +/- 10.6 min, respectively, P < 0.001.
Insulin-induced hypoglycemia increases the gastric emptying rate in healthy subjects.
比较健康受试者在血糖正常和胰岛素诱导的低血糖状态下的胃排空率。
对8名健康受试者，采用放射性核素闪烁扫描技术，通过胰岛素-葡萄糖钳夹分别控制血糖正常和低血糖状态，评估同位素标记餐的胃排空率。
固体相从胃中排空50%测试餐的平均时间（T50），血糖正常时为43.0±20.0分钟，低血糖时为16.3±6.6分钟，P<0.001。液体相的平均T50分别为38.0±21.2分钟和15.4±10.6分钟，P<0.001。
胰岛素诱导的低血糖会增加健康受试者的胃排空率。
