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[羊水过多及其与先天性畸形的关系:超声诊断]

[Polyhydramnios and its relationship with congenital malformations: ultrasonographic diagnosis].

作者信息

Gaxiola Castro R, Gamboa R, Fajardo Dueñas S, Castellanos González J A, Gaona Flores R

机构信息

Servicio de diagnóstico materno fetal, Nuevo Hospital Civil de Guadalajara Universidad de Guadalajara.

出版信息

Ginecol Obstet Mex. 1995 Dec;63:505-8.

PMID:8586296
Abstract

We analyzed the occurrence of polyhydramnios during pregnancy and to indicate the association with congenital abnormalities of the product and maternal alterations. A retrospective descriptive and transversal study was performed which included 6087 pregnant patients who were submitted to ultrasonographic studies from January 1, 1991 to December 31, 1993. The final sample consisted of 72 patients with criteria of polyhydramnios and who had a complete, clinical history, specific data concerning the reproductive history and maternal risk factors associated with polyhydramnios and fetal malformations was compiled. The occurrence of polyhydramnios during pregnancy was 1.1% and the association with congenital malformations was 13.8%, being the majority neural tube defects. The maternal alterations were related in 13.7% to polyhydramnios, being primary cause gestational diabetes. Anencephalia presented a significant statistics (p < 0.05). The occurrence of polyhydramnios is low in obstetric patients. Neural tube defects such as anencephalia are the primary fetal defects. Gestational diabetes and multiple gestations are the more significant maternal alterations.

摘要

我们分析了孕期羊水过多的发生率,并指出其与胎儿先天性异常及母体改变之间的关联。我们进行了一项回顾性描述性横断面研究,纳入了1991年1月1日至1993年12月31日期间接受超声检查的6087例孕妇。最终样本包括72例符合羊水过多标准的患者,收集了她们完整的临床病史、生殖史的具体数据以及与羊水过多和胎儿畸形相关的母体危险因素。孕期羊水过多的发生率为1.1%,与先天性畸形的关联率为13.8%,其中大多数为神经管缺陷。13.7%的母体改变与羊水过多有关,主要原因是妊娠期糖尿病。无脑儿呈现出显著的统计学差异(p<0.05)。产科患者中羊水过多的发生率较低。神经管缺陷如无脑儿是主要的胎儿缺陷。妊娠期糖尿病和多胎妊娠是更显著的母体改变。

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Ginecol Obstet Mex. 1995 Dec;63:505-8.
2
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