Romero Gutierrez G, Fuentes Paramo H, Membrila Alfaro E, Vargas Huerta M
Hospital de Gineco-Obstetricia del Centro Médico del Instituto Mexicano del Seguro Social, León, Guanajuato.
Ginecol Obstet Mex. 1996 Jan;64:1-5.
We carried out a prospective study at the Hospital de Gineco-Obstetricia del Instituto Mexicano del Seguro Social, in León, Guanajuato in order to evaluate the association between polyhydramnios and fetal congenital anomalies. 200 women were included, 100 with polyhydramnios and 100 with normal amniotic fluid (control group). The diagnosis of polyhydramnios was made with ultrasound scanning using maximum vertical pocket technique and amniotic fluid index. The patients with polyhydramnios had an average maximum vertical pocket of 9.3 centimeters and amniotic fluid index of 27.0 centimeters. In patients with polyhydramnios 24 cases of congenital malformations were found, and none in patients with normal amniotic fluid (P < 0.01). The most common fetal anomalies were: esophageal atresia (25%), anencephaly (21%) and ductus arteriosus (21%). There were six perinatal deaths in the group of patients with polyhydramnios, five of them had congenital abnormalities, on the other hand in the control group there were no perinatal deaths (P < 0.01). Owing to the signifficative association between polyhydramnios and congenital anomalies, we suggest to reinforce the ultrasound evaluation in order to detect these abnormalities and to offer an early treatment and therefore a better prognosis to the fetus.
我们在墨西哥社会保障局莱昂瓜纳华托妇产科医院进行了一项前瞻性研究，以评估羊水过多与胎儿先天性异常之间的关联。研究纳入了200名女性，其中100名羊水过多，100名羊水正常（对照组）。羊水过多的诊断采用超声扫描，运用最大垂直羊水池技术和羊水指数。羊水过多的患者平均最大垂直羊水池为9.3厘米，羊水指数为27.0厘米。在羊水过多的患者中发现24例先天性畸形，而羊水正常的患者未发现（P<0.01）。最常见的胎儿异常为：食管闭锁（25%）、无脑儿（21%）和动脉导管未闭（21%）。羊水过多组有6例围产期死亡，其中5例有先天性异常，而对照组无围产期死亡（P<0.01）。鉴于羊水过多与先天性异常之间存在显著关联，我们建议加强超声评估，以检测这些异常并提供早期治疗，从而改善胎儿预后。
