Webb C H, Hogg G M
Royal Hospitals Trust, Kelvin Laboratories, Department of Bacteriology, Belfast, Northern Ireland, UK.
J Hosp Infect. 1995 Nov;31(3):219-24. doi: 10.1016/0195-6701(95)90069-1.
The use of closed multi-use tracheal suction systems in ventilated patients is increasingly popular as it offers a number of potential physiological and microbiological advantages. As the use of these systems has been associated with an increased prevalence of tracheal colonization, effective self-cleaning mechanisms employed in these catheters are necessary. Using an in-vitro model we assessed the degree of catheter colonization in two multi-use catheter systems; Stericath and Trach-Care. Fifty of each catheter type were tested for colonization with five challenge organisms: Staphylococcus aureus (NCTC 6571); Pseudomonas aeruginosa (NCTC 10662); Haemophilus influenzae type b; S. epidermidis (slime producer); and S. epidermidis (slime non-producer). All five challenge strains had colonized both catheter types after 24 h and all 100 catheter tips were colonized. The extent and density of colonization was variable and interspecies variation in the pattern of catheter colonization was observed. The mean colonized lengths of Stericath catheters was 10.9 +/- 1.4 cm and of Trach-Care 2.7 +/- 1.3 cm (P < 0.0001).
在机械通气患者中使用封闭式多用途气管吸引系统越来越普遍，因为它具有一些潜在的生理和微生物学优势。由于这些系统的使用与气管定植的发生率增加有关，因此这些导管采用有效的自清洁机制很有必要。我们使用体外模型评估了两种多用途导管系统（Stericath和Trach-Care）中导管的定植程度。每种导管类型各50根，用五种挑战微生物进行定植测试：金黄色葡萄球菌（NCTC 6571）；铜绿假单胞菌（NCTC 10662）；b型流感嗜血杆菌；表皮葡萄球菌（产黏液）；以及表皮葡萄球菌（不产黏液）。24小时后，所有五种挑战菌株均在两种导管类型上定植，所有100个导管尖端均被定植。定植的程度和密度各不相同，并且观察到导管定植模式存在种间差异。Stericath导管的平均定植长度为10.9±1.4厘米，Trach-Care导管的平均定植长度为2.7±1.3厘米（P<0.0001）。
