Kodama H
Department of Pediatrics, Teikyo University School of Medicine.
Nihon Rinsho. 1996 Jan;54(1):46-51.
The effects of zinc, iron, copper and selenium on the immune system are reviewed. Among the essential trace elements in humans, zinc, iron, copper and selenium are essential for the integrity and optimum function of the immunity. Although each element has different functions in the immune system, the deficiencies in each of these elements mainly causes the dysfunction of cell-mediated immunity. Deficiencies do not significantly effect the B cell function. These immunological abnormalities can be improved by supplementation of deficient elements. However, excess supplementation also impairs the immune system. Therefore, a proper balance of these elements is essential for maintenance of immunocompetence.
综述了锌、铁、铜和硒对免疫系统的影响。在人体必需的微量元素中，锌、铁、铜和硒对于免疫系统的完整性和最佳功能至关重要。尽管每种元素在免疫系统中具有不同的功能，但这些元素中的每一种缺乏主要会导致细胞介导免疫功能障碍。缺乏并不会显著影响B细胞功能。通过补充缺乏的元素可以改善这些免疫异常。然而，过量补充也会损害免疫系统。因此，这些元素的适当平衡对于维持免疫能力至关重要。
