Yonekura Y
Biomedical Imaging Research Center, Fukui Medical School.
Kaku Igaku. 1995 Dec;32(12):1375-9.
Radionuclide methods, including positron emission tomography (PET) and single photon emission computed tomography (SPECT), can visualize brain function by assessment of regional changes in blood flow and metabolism and measurement of neurotransmission function. Brain utilizes glucose as a major substrate for energy metabolism, and PET and SPECT images of blood flow and metabolism can be used as indices of neuronal activity. On the other hand, various radioligands have been developed for evaluation of pre- and post-synaptic neurons using PET and SPECT. The clinical role neuroreceptor imaging is now under investigation.
放射性核素方法，包括正电子发射断层扫描（PET）和单光子发射计算机断层扫描（SPECT），可以通过评估血流和代谢的区域变化以及测量神经传递功能来可视化脑功能。大脑利用葡萄糖作为能量代谢的主要底物，血流和代谢的PET和SPECT图像可用作神经元活动的指标。另一方面，已经开发出各种放射性配体，用于使用PET和SPECT评估突触前和突触后神经元。神经受体成像的临床作用目前正在研究中。
