Khrapova N P, Tikhonov N G, Prokhvatilova E V, Kulakov M Ia
Med Parazitol (Mosk). 1995 Oct-Dec(4):49-53.
The paper summarizes the data concerning the production and study of monoclonal antibodies (MAb) to the diagnostically significant glanders and melioidosis bacillus antigens. It evaluates the efficiency of using MAb in the gel immunodiffusion and agglutination tests as a basis of new-generation preparations for fluorescent antibody assay, indirect hemagglutination test which are used while detecting and identifying pathogenic pseudomonads. The paper defines the quality indices for monoclonal luminescent immunoglobulins and provides evidence for the benefits of monoclonal diagnostic agents over polyclonal analogues.
本文总结了有关针对具有诊断意义的鼻疽和类鼻疽杆菌抗原生产及研究单克隆抗体（MAb）的数据。评估了在凝胶免疫扩散和凝集试验中使用单克隆抗体作为新一代荧光抗体检测制剂、间接血凝试验的基础的效率，这些试验用于检测和鉴定致病性假单胞菌。本文定义了单克隆发光免疫球蛋白的质量指标，并提供了单克隆诊断试剂优于多克隆类似物的证据。
