Rummeny E J, Reimer P, Daldrup H, Peters P E
Institut für Klinische Radiologie, Westfälische Wilhelms-Universität, Münster.
Radiologe. 1995 Nov;35(11 Suppl 2):S252-8.
Accurate detection of liver metastases in patients with known primary tumors is often essential for therapeutic decision making. Compared to conventional contrast media-enhanced CT unenhanced MRI seems to be slightly superior for the detection of small focal liver lesions. However, intraoperative US and CTAP show higher sensitivities for lesion detection but use of these techniques is limited because of their invasive character. The new superparamagnetic MR contrast medium ENDOREM improves the number of liver lesions detected significantly as compared to unenhanced MRI. Furthermore, as shown recently, ENDOREM-enhanced MRI may be as sensitive as CTAP. Thus, ENDOREM is useful for preoperative staging of liver tumors due to improvement in lesion detection and delineation of the hepatic vascular system.
对于已知原发性肿瘤的患者，准确检测肝转移灶对于治疗决策通常至关重要。与传统的对比剂增强CT相比，平扫MRI在检测小的局灶性肝病变方面似乎略具优势。然而，术中超声和CT动脉门静脉造影对病变检测具有更高的敏感性，但由于其侵入性，这些技术的应用受到限制。新型超顺磁性MR对比剂恩度（ENDOREM）与平扫MRI相比，显著提高了检测到的肝病变数量。此外，最近的研究表明，恩度增强MRI可能与CT动脉门静脉造影一样敏感。因此，恩度有助于肝肿瘤的术前分期，因为它能改善病变检测并清晰显示肝血管系统。
