Senéterre E, Taourel P, Bouvier Y, Pradel J, Van Beers B, Daures J P, Pringot J, Mathieu D, Bruel J M
Department of Medical Imaging, Hôpital St Eloi, Montpellier, France.
Radiology. 1996 Sep;200(3):785-92. doi: 10.1148/radiology.200.3.8756932.
To prospectively compare the diagnostic accuracy of computed tomography (CT) during arterial portography (CTAP) with that of unenhanced and ferumoxides-enhanced magnetic resonance (MR) imaging at 0.5 T in the detection of hepatic metastases.
Four pairs of radiologists independently assessed the metastatic involvement of 134 hepatic segments (31 with and 103 without metastasis) in 17 patients at unenhanced and ferumoxides-enhanced spin-echo and gradient-echo MR imaging (alone and in combination) and at CTAP. The diagnostic performance of the various imaging modalities was assessed by means of receiver operating characteristic analysis.
The accuracy of CTAP, unenhanced MR imaging (combined unenhanced sequences), and ferumoxides-enhanced MR imaging (combined contrast material-enhanced sequences) was 0.925, 0.908, and 0.951, respectively. Ferumoxides-enhanced MR imaging was significantly more accurate (P < .05) than unenhanced MR imaging and CTAP. When 14 segments containing cysts were excluded, the difference between ferumoxides-enhanced MR imaging and CTAP was no longer statistically significant (P = .1).
Ferumoxides-enhanced MR imaging is more accurate than unenhanced MR imaging and at least as accurate as CTAP for the detection of hepatic metastases.
前瞻性比较动脉期门静脉造影CT（CTAP）与0.5T场强下未增强及超顺磁性氧化铁增强磁共振成像（MR）检测肝转移瘤的诊断准确性。
四组放射科医生独立评估17例患者134个肝段（31个有转移，103个无转移）在未增强及超顺磁性氧化铁增强自旋回波和梯度回波MR成像（单独及联合）以及CTAP时的转移情况。通过接受者操作特征分析评估各种成像方式的诊断性能。
CTAP、未增强MR成像（联合未增强序列）以及超顺磁性氧化铁增强MR成像（联合对比剂增强序列）的准确性分别为0.925、0.908和0.951。超顺磁性氧化铁增强MR成像的准确性显著高于未增强MR成像和CTAP（P <.05）。当排除14个含囊肿的肝段后，超顺磁性氧化铁增强MR成像与CTAP之间的差异不再具有统计学意义（P =.1）。
超顺磁性氧化铁增强MR成像在检测肝转移瘤方面比未增强MR成像更准确，且至少与CTAP一样准确。
