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用更昔洛韦成功治疗免疫功能正常成人的播散性巨细胞病毒感染。

Disseminated cytomegalovirus infection in an immunocompetent adult successfully treated with ganciclovir.

作者信息

López-Contreras J, Ris J, Domingo P, Puig M, Rabella N, Nolla J

机构信息

Department of Internal Medicine, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Spain.

出版信息

Scand J Infect Dis. 1995;27(5):523-5. doi: 10.3109/00365549509047059.

Abstract

We report the case of a previously healthy man who suffered a disseminated cytomegalovirus infection. He presented with prolonged fever, weight loss of 8 kg, anicteric hepatitis, upper digestive tract bleeding from gastric ulcers, acute polyneuritis and bilateral retinitis. Immunodeficiency was not detected either during admission or during a 3-year follow-up period. The patient was treated with ganciclovir (5 mg/kg BID) during 4 weeks with a favourable clinical outcome. To our knowledge, this is the first reported case with such characteristics.

摘要

我们报告一例既往健康的男性患者,其发生了播散性巨细胞病毒感染。他出现持续发热、体重减轻8千克、无黄疸型肝炎、胃溃疡导致的上消化道出血、急性多发性神经炎和双侧视网膜炎。入院期间及3年随访期间均未检测到免疫缺陷。患者接受了4周的更昔洛韦治疗(5毫克/千克,每日两次),临床结果良好。据我们所知,这是首例具有此类特征的报告病例。

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