Tajunisah I, Reddy S C, Tan L H
Department of Ophthalmology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Int Ophthalmol. 2009 Apr;29(2):85-90. doi: 10.1007/s10792-007-9171-5. Epub 2007 Nov 16.
A rare case of acute retinal necrosis caused by cytomegalovirus in an immunocompetent adult, diagnosed by polymerase chain reaction of vitreous aspirate, with good visual outcome after intravitreal and intravenous ganciclovir and oral prednisolone therapy, is reported. A 50-year-old healthy lady presented with redness and diminution of vision in her right eye of 10 days duration. She had anterior chamber inflammation, marked vitritis, and anterior retinal necrosis in the right eye. Blood and other investigations did not reveal any infectious diseases and HIV testing was negative. The retinal lesions and panuveitis resolved with treatment. Two months later she developed retinal detachment which was treated successfully. The best-corrected vision was 6/12 in the right eye. Seven cases of cytomegalovirus ocular infection in immunocompetent healthy adults, reported in the literature, were reviewed. The different presentations of this disease and the importance of suspecting this causative agent are highlighted.
报道了1例免疫功能正常的成年人由巨细胞病毒引起的急性视网膜坏死罕见病例，通过玻璃体抽吸物聚合酶链反应确诊，经玻璃体内及静脉注射更昔洛韦和口服泼尼松龙治疗后视力恢复良好。一名50岁健康女性，右眼出现眼红和视力下降10天。她右眼有前房炎症、明显的玻璃体炎和视网膜前坏死。血液及其他检查未发现任何传染病，HIV检测呈阴性。经治疗后视网膜病变和全葡萄膜炎消退。两个月后她发生视网膜脱离，经成功治疗。右眼最佳矫正视力为6/12。回顾了文献中报道的7例免疫功能正常的健康成年人巨细胞病毒眼部感染病例。强调了该疾病的不同表现以及怀疑该病原体的重要性。
