Weingärtner K, Gerharz E W, Bittinger A, Rosai J, Leppek R, Riedmiller H
Department of Urology, Philipps University Medical School, Marburg, Germany.
Urol Int. 1995;55(4):232-5. doi: 10.1159/000282795.
Primary carcinoma of the adrenal cortex is an extremely rare neoplasm, accounting for an estimated 0.05-0.2% of all malignancies. Hormonally functioning tumors occur in about 50% of patients with Cushing's syndrome (50%), virilism (30%) and feminization (12%) being the most common clinical manifestations. Isolated aldosteronism caused by adrenocortical carcinoma is found in about 1-3% in patients with the clinical signs of Conn's syndrome. The only preoperative feature suggesting malignancy is a size of more than 5 cm in computed tomography. We report a rare case of a 29-year-old man with biochemically proven primary aldosteronism as the unique manifestation of a carcinoma of the right adrenal cortex.
肾上腺皮质原发性癌是一种极其罕见的肿瘤，约占所有恶性肿瘤的0.05 - 0.2%。约50%患有库欣综合征的患者存在具有激素功能的肿瘤，其中最常见的临床表现为库欣综合征（50%）、男性化（30%）和女性化（12%）。肾上腺皮质癌引起的孤立性醛固酮增多症在具有Conn综合征临床体征的患者中约占1 - 3%。术前提示恶性的唯一特征是计算机断层扫描显示肿瘤大小超过5 cm。我们报告一例罕见病例，一名29岁男性，经生化检查证实为原发性醛固酮增多症，这是右肾上腺皮质癌的唯一表现。
