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腿部溃疡复发的危险因素:两种压力袜的随机试验

Risk factors for leg ulcer recurrence: a randomized trial of two types of compression stocking.

作者信息

Franks P J, Oldroyd M I, Dickson D, Sharp E J, Moffatt C J

机构信息

Centre for Research and Implementation of Clinical Practice, Royal Masonic Hospital, London.

出版信息

Age Ageing. 1995 Nov;24(6):490-4. doi: 10.1093/ageing/24.6.490.

DOI:10.1093/ageing/24.6.490
PMID:8588538
Abstract

Patients with recently healed leg ulceration were entered into a study of leg ulcer recurrence. In all, 188 patients [69% women, mean age = 72 (SD = 12) years] were entered into the study, of whom 166 were considered suitable for ready-made stockings and were randomized to one of two class II below-knee compression stockings and followed for at least 18 months. The remaining patients required either made-to-measure stockings (5) or could not tolerate stockings owing to friable skin and were treated by other methods (17). Overall cumulative recurrence rate was 26% after 1 year and 31% at 18 months. Independent risk factors for (RR = 2.34, p = 0.021) and unsuitability for stockings (RR = 2.52, p = 0.013). The randomized groups had similar stockings, 25 (15%) could not put their stockings on at all and 43 (26%) were only able to put them on with great difficulty. The two stocking types differed significantly in this regard when analysed for trend.

摘要

近期腿部溃疡已愈合的患者被纳入一项腿部溃疡复发的研究。共有188名患者[69%为女性,平均年龄=72(标准差=12)岁]进入该研究,其中166名被认为适合使用成品弹力袜,并被随机分为两种II级膝下压力袜中的一种,随访至少18个月。其余患者要么需要定制弹力袜(5名),要么因皮肤脆弱无法耐受弹力袜,采用其他方法治疗(17名)。1年后总体累积复发率为26%,18个月时为31%。复发的独立危险因素为(相对风险=2.34,p=0.021)以及不适合使用弹力袜(相对风险=2.52,p=0.013)。随机分组的患者使用的弹力袜类似,25名(15%)根本无法穿上弹力袜,43名(26%)只能非常困难地穿上。分析趋势时,两种弹力袜类型在这方面存在显著差异。

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