Coleman G B, Kaltenbach J A, Falzarano P R
Department of Otolaryngology-Head and Neck Surgery, Wayne State University School of Medicine, Detroit, Michigan, USA.
Am J Otol. 1995 Sep;16(5):620-7.
The various stages of tectorial membrane development were observed postnatally, using the scanning electron microscope. Hamster cochleas were obtained at 2-day intervals beginning with the day of birth and ending at 22 days after birth. Changes in the tectorial membrane structure were quantified by studying the transformation from a pattern of widely spaced fiber bundles to the continuous sheet-like membrane of the adult. Specifically, this transformation was quantified by summing the widths of the fiber bundles along a 25-micron traverse drawn parallel to the outer edge of the minor tectorial membrane, overlying the middle hair cell row. Such measures were performed at different locations along the cochlear spiral. The results indicate a base-to-apex progression of tectorial membrane development with attainment of mature characteristics between 18 and 22 days after birth. Comparison with previous studies indicate that the maturation of the tectorial membrane coincides with a period of major improvement in evoked potential thresholds in the central auditory system.
利用扫描电子显微镜对出生后盖膜发育的各个阶段进行了观察。从出生日开始，每隔2天获取仓鼠耳蜗，直至出生后22天。通过研究从宽间距纤维束模式到成年连续片状膜的转变，对盖膜结构的变化进行了量化。具体而言，通过沿着与覆盖中毛细胞排的小盖膜外边缘平行绘制的25微米横切面，将纤维束的宽度相加来量化这种转变。在耳蜗螺旋的不同位置进行了此类测量。结果表明盖膜发育从基部向顶部推进，在出生后18至22天达到成熟特征。与先前研究的比较表明，盖膜的成熟与中枢听觉系统诱发电位阈值的主要改善期相吻合。
