Poni E, Granero R, Escobar B
Departamento de Patología y Anatomía Humana, Universidad de Loma Linda, California, USA.
Invest Clin. 1995 Dec;36(4):163-72.
Stroke, the 5th. cause of death in Venezuela, has been associated to cerebral infarction. However, there is little information concerning lethality factors. 33 atherothrombotic subtype stroke patients, 31 (96%) Latino and 2(4%) white, were admitted into a prospective study to analyze the role of 11 mortality risk factors for those patients. A mortality relative risk (RR) > 1.5 or < 1 (protective) was considered clinically important if 1 was excluded from the 95% confidence interval (95%CI). The Mantel-Haenszel Chi-square procedure was use to test statistical significance (p < 0.05). Mortality RR for patients age 65 and over (RR = 2.95) and 4 year mortality RR for male patients (RR = 2.04) were clinically and statistically significant. History of high blood pressure was protective (RR = 0.62) probably due to good medical control. Cumulative mortality was higher than that of comparable studies, even from the first week of follow-up, reaching 67% at the 4th year.
中风是委内瑞拉第五大死因，一直与脑梗死相关。然而，关于致死因素的信息很少。33例动脉粥样硬化血栓形成亚型中风患者被纳入一项前瞻性研究，以分析11种死亡风险因素对这些患者的作用，其中31例（96%）为拉丁裔，2例（4%）为白人。如果95%置信区间（95%CI）不包括1，则将相对死亡风险（RR）>1.5或<1（具有保护作用）视为具有临床重要性。采用Mantel-Haenszel卡方检验来检验统计学显著性（p<0.05）。65岁及以上患者的死亡RR（RR=2.95）以及男性患者的4年死亡RR（RR=2.04）在临床和统计学上均具有显著性。高血压病史具有保护作用（RR=0.62），可能是由于良好的医疗控制。累积死亡率高于同类研究，甚至从随访的第一周起就如此，在第4年达到67%。
