Kuyama J, Fushino M, Take H, Kanayama Y
Department of Internal Medicine, Toyonaka Municipal Hospital, Hyogo, Japan.
Int J Hematol. 1995 Dec;62(4):243-6. doi: 10.1016/0925-5710(95)00409-2.
A 63-year-old man with refractory anemia with excess of blasts in transformation exhibited erythroid hyperplasia, dyserythropoiesis, a del(20q) abnormality, susceptibility to bacterial infections, and a relatively short survival. Phagocytosis of erythrocytes by blast cells was observed. Erythrophagocytosis was also seen in myeloid cells, including promyelocytes, myelocytes, metamyelocytes and neutrophils. Neither the monocytes nor the macrophages showed erythrophagocytosis. This is the first report of erythrophagocytosis by blasts and myeloid cells in a patient with myelodysplastic syndrome.
一名63岁的转化型原始细胞过多难治性贫血男性患者表现出红系增生、红系造血异常、20号染色体长臂缺失异常、易发生细菌感染以及生存期相对较短。观察到原始细胞对红细胞的吞噬现象。在包括早幼粒细胞、中幼粒细胞、晚幼粒细胞和中性粒细胞在内的髓系细胞中也可见红细胞吞噬现象。单核细胞和巨噬细胞均未表现出红细胞吞噬现象。这是关于骨髓增生异常综合征患者中原始细胞和髓系细胞出现红细胞吞噬现象的首例报道。
