Harrison Aradhana, Chandra Dinesh, Kakkar Naveen, Das Sheila, John M Joseph
Department of Pathology, Christian Medical College & Hospital, Brown Road, Ludhiana, 141 008 Punjab India.
Department of Clinical Hematology, Hemato-Oncology and Bone Marrow (Stem cell), Transplant Unit, Christian Medical College & Hospital, Brown Road, Ludhiana, 141 008 Punjab India.
Indian J Hematol Blood Transfus. 2016 Jun;32(Suppl 1):23-5. doi: 10.1007/s12288-015-0531-4. Epub 2015 Mar 18.
Hemophagocytosis shows engulfment of hematopoietic cells by histiocytes and is a property generally associated with cells of the histiocytic lineage. It can be familial or is seen in a wide spectrum of acquired disorders. Hemophagocytosis by leukemic blasts is an uncommon phenomenon and has been reported mainly in acute myeloid leukemia. Its association with acute lymphoblastic leukemia is rare. We present a case of hemophagocytosis by blasts in the bone marrow in a 11 year old boy with T cell-acute lymphoblastic leukemia.
噬血细胞现象表现为组织细胞吞噬造血细胞，这一特性通常与组织细胞谱系的细胞相关。它可以是家族性的，也可见于多种获得性疾病。白血病原始细胞的噬血细胞现象是一种罕见现象，主要在急性髓系白血病中报道过。其与急性淋巴细胞白血病的关联很少见。我们报告一例11岁患T细胞急性淋巴细胞白血病男孩骨髓中原始细胞出现噬血细胞现象的病例。
