Schwingshandl J, Borkenstein M
Department of Paediatrics, University of Graz, Austria.
Int J Obes Relat Metab Disord. 1995 Oct;19(10):752-5.
To study the changes in body composition during a weight reduction program in obese children and adolescents.
A short-term longitudinal study.
Forty-one obese children and adolescents (19 M, 22F, age 8.5-14.8 [median 11.8] years.
Lean body mass (LBM) was estimated from Resistance Index (RI) obtained by Bioelectrical Impedance Analysis (BIA) before and after the 3 week program.
Mean percentage weight for height at baseline was 151 (s.d. 20)% and significantly decreased at the end of the three weeks (139 (s.d. 18)%, P = 0.005). The mean percentage body fat also decreased (from 46.0 s.d. 5.8% to 41.5 s.d. 6.5%, P = 0.0015). All individuals lost body fat during the three weeks, whereas the change in LBM was heterogeneous. The individual change in body fat was inversely correlated with the change in LBM (r = -0.64, P = 0.0001). After 4 months, 18 out of the 41 children could be reevaluated for height and weight. The regain in body weight during these 4 months was inversely correlated with the change in LBM during the weight reduction program (r = -0.55, P = 0.018).
Changes in LBM during a weight reduction program can predict the short term result those children who manage to increase LBM having the greatest reduction in body fat. Changes in LBM during weight reduction seem also to predict the longterm outcome, a reduction in LBM being associated with greater regain of weight. Weight reduction programs for obese children should focus not only on weight loss but also on maintenance or increase of lean body mass to improve longterm results.
研究肥胖儿童和青少年在减肥计划期间身体成分的变化。
短期纵向研究。
41名肥胖儿童和青少年（19名男性，22名女性，年龄8.5 - 14.8岁[中位数11.8岁]）。
在为期3周的计划前后，通过生物电阻抗分析（BIA）获得的电阻抗指数（RI）估算去脂体重（LBM）。
基线时身高体重平均百分比为151（标准差20）%，在三周结束时显著下降（139（标准差18）%，P = 0.005）。平均体脂百分比也下降了（从46.0（标准差5.8）%降至41.5（标准差6.5）%，P = 0.0015）。在三周内所有个体都减少了体脂，而去脂体重的变化是异质性的。个体体脂变化与去脂体重变化呈负相关（r = -0.64，P = 0.0001）。4个月后，41名儿童中有18名可重新评估身高和体重。这4个月期间体重的恢复与减肥计划期间去脂体重的变化呈负相关（r = -0.55，P = 0.018）。
减肥计划期间去脂体重的变化可以预测短期结果，即那些成功增加去脂体重的儿童体脂减少最多。减肥期间去脂体重的变化似乎也能预测长期结果，去脂体重减少与体重更大程度的恢复相关。肥胖儿童的减肥计划不仅应关注体重减轻，还应关注去脂体重的维持或增加，以改善长期效果。
