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青少年超重与肥胖的治疗。

Treatment of adolescent overweight and obesity.

作者信息

Tsiros Margarita D, Sinn Natalie, Coates Alison M, Howe Peter R C, Buckley Jonathan D

机构信息

Nutritional Physiology Research Centre and ATN Centre for Metabolic Fitness, School of Health Sciences, University of South Australia, P.O. Box 2471, Adelaide, SA 5001, Australia.

出版信息

Eur J Pediatr. 2008 Jan;167(1):9-16. doi: 10.1007/s00431-007-0575-z. Epub 2007 Nov 1.

Abstract

Adolescence is a vulnerable period for the development of obesity, and adolescent weight tracks strongly into adulthood. Previous reviews of treatment strategies have failed to discriminate between adolescents and children, thereby, disregarding the uniqueness of this population. Hence, this review aims to summarise the evidence for treatment approaches for adolescent obesity. Pubmed, OVID, EBSCOhost and Google Scholar were searched for randomised controlled trials, meta-analyses and systematic reviews testing treatments for overweight/obese adolescents (aged 12-19 years), published from 1982-2006 in English. Eligible studies had to assess either weight, percentage overweight, body mass index (BMI) or body fat. Thirty-four randomised controlled trials were eligible. The results of this review indicate that the safety and efficacy of surgical and pharmacotherapy treatments for adolescent obesity is uncertain. Diet and physical activity approaches may improve obese status in the short term. However, obesity interventions appear more effective when strategies are combined, rather than when used in isolation. Psychological interventions, such as behavioural and cognitive behavioural therapy, show promise in achieving the necessary lifestyle changes for obesity reduction; however, long-term follow-up studies are needed. There were multiple limitations in appraising the literature. Inconsistent definitions of overweight/obesity make comparisons between studies difficult. Many studies have not used direct adiposity measures, have failed to assess pubertal status or have not used an exclusive adolescent sample. We conclude that, despite these limitations, current evidence indicates that behavioural and cognitive behavioural strategies combined with diet and physical activity approaches may assist in reducing adolescent obesity,although long-term follow-up studies are needed.

摘要

青春期是肥胖发展的一个脆弱时期,青少年体重状况会强烈影响到成年期。以往对治疗策略的综述未能区分青少年和儿童,因此忽视了这一人群的独特性。因此,本综述旨在总结青少年肥胖治疗方法的证据。检索了PubMed、OVID、EBSCOhost和谷歌学术,查找1982年至2006年期间以英文发表的针对超重/肥胖青少年(12至19岁)测试治疗方法的随机对照试验、荟萃分析和系统评价。符合条件的研究必须评估体重、超重百分比、体重指数(BMI)或体脂。有34项随机对照试验符合条件。本综述结果表明,手术和药物治疗青少年肥胖的安全性和有效性尚不确定。饮食和体育活动方法可能在短期内改善肥胖状况。然而,当各种策略联合使用而非单独使用时,肥胖干预措施似乎更有效。心理干预,如行为疗法和认知行为疗法,在实现减少肥胖所需的生活方式改变方面显示出前景;然而,需要长期随访研究。在评估文献时有多个局限性。超重/肥胖的定义不一致使得研究之间难以进行比较。许多研究没有使用直接的肥胖测量方法,没有评估青春期状态,或者没有使用专门的青少年样本。我们得出结论,尽管存在这些局限性,但目前的证据表明,行为和认知行为策略与饮食和体育活动方法相结合可能有助于减少青少年肥胖,不过需要长期随访研究。

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