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Progesterone-induced DNA polymerase activity in full-grown oocytes of Xenopus laevis (1).

作者信息

Grippo P, Locorotondo G, Taddei C

出版信息

J Exp Zool. 1977 Apr;200(1):143-8. doi: 10.1002/jez.1402000117.

DOI:10.1002/jez.1402000117
PMID:859007
Abstract

DNA polymerase activity increases in full-grown oocytes of Xenopus laevis during in vitro progesterone-induced maturation. This increase is inhibited by cycloheximide. The presence of the oocyte's nucleus (germinal vesicle) seems essential for the induction of this increase: in previously enucleated oocytes, the level of DNA polymerase activity does not change during progesterone treatment. Furthermore, a new form of DNA polymerase is detectable by DEAE chromatography in in vitro matured oocytes.

摘要

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