Kane R D, Paulson D F
J Urol. 1977 May;117(5):618-21. doi: 10.1016/s0022-5347(17)58556-0.
Radioisotopic bone scans and metastatic bone surveys were conducted on patients with endocrine-unresponsive prostatic adenocarcinoma undergoing multiple drug chemotherapy. Three types of bone scans were observed--type I scans were characterized by asymmetric radioisotope activity and normal renal imaging, type II was characterized by symmetrical skeletal uptake and faint or absent renal imaging and type III showed symmetrical skeletal uptake with normal renal imaging and was interpreted as normal, although the bone surveys showed diffuse osteoblastic disease. The appearance of a type II scan was a grave prognostic indicator.
对接受多种药物化疗的内分泌无反应性前列腺腺癌患者进行了放射性同位素骨扫描和转移性骨检查。观察到三种类型的骨扫描——I型扫描的特征是放射性同位素活性不对称且肾脏显像正常，II型的特征是骨骼摄取对称且肾脏显像模糊或无显像，III型显示骨骼摄取对称且肾脏显像正常，尽管骨检查显示有弥漫性成骨疾病，但仍被解释为正常。II型扫描的出现是一个严重的预后指标。
