Corrie D, Timmons J H, Bauman J M, Thompson I M
Department of Surgery, Brooke Army Medical Center, Fort Sam Houston, Texas.
Cancer. 1988 Jun 15;61(12):2453-4. doi: 10.1002/1097-0142(19880615)61:12<2453::aid-cncr2820611211>3.0.co;2-p.
Three hundred fifteen radioisotopic bone scans ranging from initial scan only to nine scans per patient, performed on 114 patients with adenocarcinoma of the prostate between 1979 and 1984, were reviewed. Seventeen patients had positive scans, ten on initial scan and seven at follow-up. Nine patients had bone pain at the time of the first positive scan and pain developed in two patients 6 months and 2 years later, respectively. The other six patients are still asymptomatic 1 to 4 years later. False-positive scans were found in six other patients. No patient with bone pain had a negative scan. We believe that routine bone scans for prostate cancer follow-up are not cost-effective unless the patient is symptomatic. Bone scans also are indicated for initial staging and to observe disease response to protocol treatment.
回顾了1979年至1984年间对114例前列腺腺癌患者进行的315次放射性核素骨扫描，扫描次数从仅进行初次扫描到每位患者进行9次扫描。17例患者扫描结果为阳性，10例初次扫描阳性，7例随访时阳性。9例患者在首次阳性扫描时有骨痛，另外2例患者分别在6个月和2年后出现疼痛。其他6例患者在1至4年后仍无症状。另外6例患者出现假阳性扫描结果。有骨痛的患者扫描结果均无阴性。我们认为，除非患者有症状，否则前列腺癌随访的常规骨扫描不具有成本效益。骨扫描也适用于初始分期以及观察疾病对方案治疗的反应。
