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[果糖胺测定作为犬糖尿病预后评估工具]

[Fructosamine determination as a tool in the prognosis of diabetes mellitus in dogs].

作者信息

Staudacher G

机构信息

Tierärztliche Klinik Dr. Staudacher, Aachen.

出版信息

Berl Munch Tierarztl Wochenschr. 1995 Nov;108(11):418-20.

PMID:8593134
Abstract

It is difficult to give the prognosis of diabetes mellitus after castration of the bitch. An algorithm using the blood glucose and fructosamine level is suggested to evaluate the prognosis of diabetes: While the algorithm classifies 19 bitches with good prognosis 18 (95%) are cured. 18 are classified with poor prognosis and all of them undergo a long difficult insulin-therapy or are not treated with success. 6 bitches are classified as indifferent, 2 of them are cured by castration, 2 are managed with insulin and 2 are treated without success. The limits can be described by the following equations: lower limit y = 5.04x + 321, upper limit y = 7.74x + 433. If blood glucose is available only in mg/dl, the equations are: lower limit y = 0.28 + 321, upper limit y = 0.43x + 433. The algorithm is statistical high significant but it should be verified by calculation of a larger number of patients.

摘要

母犬去势后糖尿病的预后难以判断。建议使用一种基于血糖和果糖胺水平的算法来评估糖尿病的预后:该算法将19只预后良好的母犬进行分类,其中18只(95%)治愈。18只被分类为预后不良,它们全部经历了漫长而艰难的胰岛素治疗,或者治疗未成功。6只母犬被分类为预后不确定,其中2只通过去势治愈,2只通过胰岛素治疗,2只治疗未成功。这些界限可以用以下方程描述:下限y = 5.04x + 321,上限y = 7.74x + 433。如果血糖仅以mg/dl为单位,方程为:下限y = 0.28x + 321,上限y = 0.43x + 433。该算法具有高度统计学意义,但应通过计算更多患者进行验证。

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