Taylor C E, Rosenthal R O, Taylor-Robinson D
Lancet. 1979 Mar 31;1(8118):700-1. doi: 10.1016/s0140-6736(79)91150-4.
The presence of allugtinins to the causative organism of contagious equine metritis (C.E.M.) in human serum has been confirmed. Agglutinins were found in the serum of 84 (37.6%) of 223 patients with non-gonococcal urethritis (N.G.U.), and in 12.5% of these patients there was a four-fold or greater rise in titre during the course of their illness. There was no evidence that these agglutinins were the result of infection by chlamydiae or ureaplasmas. Certain patients with these agglutinins seemed to respond better to therapy with antibiotics to which the C.E.M. bacterium is susceptible in vitro than did patients in whom these agglutinins were not found. The findings suggest that the C.E.M. bacterium or a microorganism related to it may be aetiologically involved in a proportion of patients with N.G.U. A search for such an organism in these patients is in progress.
已证实在人血清中存在针对马传染性子宫炎（C.E.M.）病原体的凝集素。在223例非淋菌性尿道炎（N.G.U.）患者中，84例（37.6%）的血清中发现了凝集素，其中12.5%的患者在病程中凝集素效价升高了四倍或更高。没有证据表明这些凝集素是由衣原体或脲原体感染所致。某些有这些凝集素的患者，相较于未发现这些凝集素的患者，似乎对C.E.M.细菌在体外敏感的抗生素治疗反应更好。这些发现表明，C.E.M.细菌或与之相关的微生物可能在部分N.G.U.患者的病因学上起作用。目前正在对这些患者进行此类病原体的搜寻。
