线粒体基因组数据库（MITOMAP）：一个人类线粒体基因组数据库。
MITOMAP: a human mitochondrial genome database.
作者信息
Kogelnik A M, Lott M T, Brown M D, Navathe S B, Wallace D C
机构信息
Department of Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.
出版信息
Nucleic Acids Res. 1996 Jan 1;24(1):177-9. doi: 10.1093/nar/24.1.177.
We have developed a comprehensive database (MITOMAP) for the human mitochondrial DNA (mtDNA), the first component of the human genome to be completely sequenced [Anderson et al. (1981) Nature 290, 457-465]. MITOMAP uses the mtDNA sequence as the unifying element for bringing together information on mitochondrial genome structure and function, pathogenic mutations and their clinical characteristics, population associated variation, and gene- gene interactions. As increasingly larger regions of the human genome are sequenced and characterized, the need for integrating such information will grow. Consequently, MITOMAP not only provides a valuable reference for the mitochondrial biologist, it may also provide a model for the development of information storage and retrieval systems for other components of the human genome.
我们已经开发了一个关于人类线粒体DNA（mtDNA）的综合数据库（MITOMAP），人类基因组的首个组成部分就是它被完全测序的[安德森等人（1981年）《自然》290卷，457 - 465页]。MITOMAP将mtDNA序列用作统一要素，以整合有关线粒体基因组结构与功能、致病突变及其临床特征、群体相关变异以及基因 - 基因相互作用的信息。随着人类基因组越来越大的区域被测序和表征，整合此类信息的需求将会增加。因此，MITOMAP不仅为线粒体生物学家提供了有价值的参考，它还可能为人类基因组其他组成部分的信息存储和检索系统的开发提供一个模型。
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