[尿酸尿路结石发病机制的流行病学研究]

[An epidemiologic study on pathogenesis of uric acid urolithiasis].

作者信息

Okabe H, Hosoya T, Ichida K, Tabe A, Saji M, Hikita M, Sakai O

机构信息

Second Department of Internal Medicine, Jikei University School of Medicine, Minato-ku, Tokyo.

出版信息

Ryumachi. 1995 Oct;35(5):773-9.

PMID:8594656

Abstract

We reviewed 5477 patients with urinary calculi who presented during the years from 1975 to 1993. During this time the percentage of calcium stones has remained at approximately 86%. However over the same period the rate of urinary calculi composed of uric acid has increased and is now about 7.2%. The number of uric acid stones has increased 3.5 times compared to 1975. 355 of 394 (90.1%) with uric acid stones are male. We believe that the increase in the numbers of patients seen with gout, hyperurisemia of a high alcohol intake.

摘要

我们回顾了1975年至1993年间出现的5477例尿路结石患者。在此期间，钙结石的比例一直保持在约86%。然而，在同一时期，由尿酸组成的尿路结石的发生率有所增加，目前约为7.2%。与1975年相比，尿酸结石的数量增加了3.5倍。394例尿酸结石患者中有355例（90.1%）为男性。我们认为痛风、高尿酸血症以及高酒精摄入量患者数量的增加是导致这一现象的原因。（注：原文最后一句表述似乎不完整，翻译时根据整体语境进行了适当补充以使逻辑更通顺）