Bobik A, McLean A J
Med J Aust. 1977 Mar 12;1(11):367-9.
A study was made of 187 patients suffering from overdosage by means of clinical records and drug analysis. Drugs were detected in 152 patients. The groups of drugs most frequently involved in these patients were sedatives (51-7%), tricyclic antidepressants (21-8%) and analgesics (11-2%). This overall pattern differed little from that determined by clinical diagnosis. However, discrepancies between clinical diagnosis and laboratory analysis were found in 43 patients. A retrospective assessment was made from clinical records of the influence of drug assay results upon clinical management. Decisions as to the need for admission to hospital and decisions relating to the management of patients suffering from overdoses of analgesics and tricyclic antidepressants were aided by drug analysis.
通过临床记录和药物分析，对187名药物过量患者进行了一项研究。在152名患者中检测到了药物。这些患者中最常涉及的药物类别是镇静剂（51.7%）、三环类抗抑郁药（21.8%）和镇痛药（11.2%）。这一总体模式与临床诊断确定的模式差异不大。然而，在43名患者中发现了临床诊断与实验室分析之间的差异。根据临床记录对药物检测结果对临床管理的影响进行了回顾性评估。药物分析有助于做出关于入院必要性的决定以及与镇痛药和三环类抗抑郁药过量患者管理相关的决定。
