Creutzig A, Freund M
Department of Angiology, Medizinische Hochschule, Hannover, Germany.
Angiology. 1996 Feb;47(2):185-7. doi: 10.1177/000331979604700210.
Side effects of long-term interferon (IFN) therapy for myeloproliferative disorders may be vasospastic Raynaud's attacks and lupus-like illness. The authors report on a woman with chronic myelogenous leukemia who experienced severe trophic lesions of the fingers after forty-nine months of IFN therapy. Digital artery occlusions could be proven arteriographically.
长期使用干扰素（IFN）治疗骨髓增殖性疾病的副作用可能包括血管痉挛性雷诺氏发作和狼疮样疾病。作者报告了一名患有慢性粒细胞白血病的女性，在接受干扰素治疗49个月后出现了严重的手指营养性病变。数字动脉闭塞可通过动脉造影证实。
