Imbert M, Jouault H, Tulliez M
Service d'hématologie biologique, Hôpital Henri-Mondor, Créteil.
Rev Prat. 1996 Jan 1;46(1):23-9.
Cytological analysis of peripheral blood and bone marrow films is a quick and simple method for diagnosis of acute leukemia. In association with cytochemistry techniques it allows the rapid identification and subsequent classification of most types of acute myeloid leukemias. Although morphological analysis can suggest the diagnosis of an acute lymphoblastic leukemia, it is necessary to have the corroborating evidence of immunological markers for confirmation. In addition, ultrastructural studies contribute to the identification of rare forms of acute myeloid leukemias (minimally differentiated, megakaryoblastic). Cytological studies have also proven useful for the follow-up activities of confirming complete remission and detecting relapses.
外周血和骨髓涂片的细胞学分析是诊断急性白血病的一种快速且简单的方法。结合细胞化学技术,它能快速识别并随后分类大多数类型的急性髓系白血病。尽管形态学分析可提示急性淋巴细胞白血病的诊断,但仍需免疫标志物的确证来确诊。此外,超微结构研究有助于识别罕见形式的急性髓系白血病(微分化型、巨核细胞型)。细胞学研究在确认完全缓解和检测复发的随访活动中也已证明是有用的。