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女性对压力的神经内分泌和免疫反应。

Neuroendocrine and immunological responses of women to stress.

作者信息

Caudell K A, Gallucci B B

机构信息

College of Nursing, University of New Mexico, USA.

出版信息

West J Nurs Res. 1995 Dec;17(6):672-92. doi: 10.1177/019394599501700607.

DOI:10.1177/019394599501700607
PMID:8597232
Abstract

Natural killer (NK) cell activity, cortisol and catecholamine levels, and physiological reactivity were examined in 15 healthy women who volunteered to take a cognitive stress test (the Stroop test). Relationships were explored among the physiological and selected psychosocial variables. Urine and blood samples were taken to examine catecholamine and cortisol concentrations and NK cell activity immediately before, immediately after, and hourly for 6 hours after the Stroop test. During the Stroop test, heart rate, skin conductance, peripheral skin temperature, and blood pressure were measured. Although skin conductance, heart rate, and blood pressure increased in response to the Stroop test, neuroendocrine values did not. Cortisol secretion decreased after the Stroop test and appeared to follow the normal circadian rhythm. NK cell activity was variable among individual participants but tended to increase over time.

摘要

对15名自愿参加认知应激测试(斯特鲁普测试)的健康女性进行了自然杀伤(NK)细胞活性、皮质醇和儿茶酚胺水平以及生理反应性的检测。探讨了生理变量与选定的心理社会变量之间的关系。在斯特鲁普测试前、测试后即刻以及测试后6小时内每小时采集尿液和血液样本,以检测儿茶酚胺和皮质醇浓度以及NK细胞活性。在斯特鲁普测试期间,测量心率、皮肤电导率、外周皮肤温度和血压。尽管皮肤电导率、心率和血压因斯特鲁普测试而升高,但神经内分泌值并未升高。斯特鲁普测试后皮质醇分泌减少,且似乎遵循正常的昼夜节律。NK细胞活性在个体参与者之间存在差异,但总体上随时间推移有增加趋势。

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