Mahoney C P, Patterson S D, Ryan J
Department of Pediatrics, Virginia Mason Medical Center, Seattle, Washington, USA.
Pediatr Pathol Lab Med. 1995 Sep-Oct;15(5):791-5. doi: 10.3109/15513819509027014.
We describe the first case of a granular cell tumor of the thyroid. The tumor appeared while a girl was receiving high-dose estrogen therapy for tall stature. The tumor, however, did not contain estrogen or progesterone receptors. Although granular cell tumors occur twice as commonly in women as in men, the results of this case study do not provide evidence that tumor growth is mediated by direct estrogen or progesterone stimulation.
我们描述了首例甲状腺颗粒细胞瘤病例。该肿瘤在一名因身材高大接受高剂量雌激素治疗的女孩身上出现。然而,该肿瘤不含雌激素或孕激素受体。尽管颗粒细胞瘤在女性中的发病率是男性的两倍,但本病例研究结果并未提供证据表明肿瘤生长是由直接的雌激素或孕激素刺激介导的。