Nielsen A L, Jensen H A, Hegbrant J, Brinkenfeldt H, Thunedborg P
Department of Nephrology, Copenhagen University Hospital, Hvidovre, Denmark.
Acta Anaesthesiol Scand Suppl. 1995;107:195-200. doi: 10.1111/j.1399-6576.1995.tb04358.x.
Hypoxia during haemodialysis, mainly acetate, has been reported several times. In our study we have monitored oxygen status during 258 bicarbonate haemodialyses. A significant drop below 80 mmHg in mean oxygen tension occurred. Mean oxygen saturation reflected this drop but did not reach levels below 90%. The mean oxygen concentration was on the whole critical low, though slightly increasing during each haemodialysis session due to ultrafiltration. It is concluded that both hypoxia and hypoxaemia do occur during bicarbonate haemodialysis. To a group of patients generally having limited cardiac reserves, a poor oxygen status is a potentially serious complication to haemodialysis. Monitoring oxygen status is thus advisable.
血液透析期间的缺氧情况，主要是由醋酸盐引起的，已经有过多次报道。在我们的研究中，我们监测了258次碳酸氢盐血液透析过程中的氧状态。平均氧分压显著降至80 mmHg以下。平均氧饱和度反映了这一下降，但未达到90%以下的水平。尽管在每次血液透析过程中由于超滤作用平均氧浓度略有增加，但总体上处于临界低水平。得出的结论是，在碳酸氢盐血液透析过程中确实会发生缺氧和低氧血症。对于一组通常心脏储备有限的患者来说，不良的氧状态是血液透析的一个潜在严重并发症。因此，建议监测氧状态。
