Nijland R, Jongsma H W, Nijhuis J G, Oeseburg B
Department of Obstetrics & Gynaecology, Faculty of Medical Sciences, University of Nijmegen, The Netherlands.
Acta Anaesthesiol Scand Suppl. 1995;107:71-6. doi: 10.1111/j.1399-6576.1995.tb04336.x.
A piglet model was used to evaluate the accuracy of a fiberoptic oximeter over a wide range of arterial oxygen saturation (SaO2) values. In eight anaesthetized piglets, the inspired oxygen concentration was varied from 30% to 6% resulting in a SaO2 range from 100% to 15%. Paired data of the Opticath fiberoptic catheter, which was placed in the descending aorta, and blood sample SaO2 values assessed by a multiwavelength oximeter, were analysed. After in vitro calibration according to the manufacturer's instruction, the fiberoptic catheter started to underestimate the SaO2 below 78%, worsening towards lower SaO2 values. The overall bias was -3.4% and the precision 3.8%. An off-line fit with a non-linear model resulted in a standard deviation of residuals of 2.6%. After several in vivo calibration adjustments when the fiberoptic oximeter deviated more than 4% from the blood sample value, the bias was eliminated over the total SaO2 range and the precision was 3.7%. The Opticath fiberoptic oximeter could have an accuracy for the whole SaO2 range between 15-100% close to the accuracy of the multiwavelength oximeter, when the fiberoptic oximeter is adapted for the underestimation below 78% SaO2.
使用仔猪模型评估光纤血氧饱和度测定仪在较宽动脉血氧饱和度（SaO2）值范围内的准确性。在8只麻醉仔猪中，将吸入氧浓度从30%变化至6%，从而使SaO2范围为100%至15%。分析了置于降主动脉的Opticath光纤导管与通过多波长血氧饱和度测定仪评估的血样SaO2值的配对数据。根据制造商说明进行体外校准后，光纤导管在SaO2低于78%时开始低估SaO2，且随着SaO2值降低情况恶化。总体偏差为 -3.4%，精密度为3.8%。采用非线性模型进行离线拟合后，残差标准差为2.6%。当光纤血氧饱和度测定仪与血样值偏差超过4%时，经过几次体内校准调整后，在整个SaO2范围内偏差被消除，精密度为3.7%。当光纤血氧饱和度测定仪针对SaO2低于78%时的低估情况进行调整后，Opticath光纤血氧饱和度测定仪在15 - 100%的整个SaO2范围内的准确性可接近多波长血氧饱和度测定仪的准确性。
