Sáchez Yus E, Requena L, Simón P, del Río E
Department of Dermatology (Hospital Universitarío San Carlos, Madrid, Spain.
Am J Dermatopathol. 1995 Jun;17(3):213-21. doi: 10.1097/00000372-199506000-00001.
Literature regarding neoplasms with sebaceous differentiation is confusing, particularly concerning the concept of sebaceous epithelioma, accepted by some observers as a specific neoplasm but defined by others as basal cell carcinoma with sebaceous differentiation and still others as sebaceous adenoma in which undifferentiated basaloid cells predominate. From our study of 19 benign sebaceous neoplasms within this spectrum and a critical review of the literature, we conclude that (a) "sebaceous epithelioma" is a nonuseful term; (b) the term "basal cell carcinoma with sebaceous differentiation" should be used only for an otherwise conventional basal cell carcinoma with histological evidence of sebaceous differentiation; (c) "sebaceous adenoma," as described by Troy and Ackerman, represent polar ends of the spectrum of a benign neoplasm with varying degrees of sebaceous differentiation, for which we propose the term "sebomatricoma"; and (d) sebomatricoma, so defined, embraces such diverse benign neoplasms with sebaceous differentiation as superficial epithelioma with sebaceous differentiation and previously "unclassifiable" sebaceous neoplasms, often found in patients with Muir-Torre syndrome or within nevus sebaceus of Jadassohn.
关于具有皮脂腺分化的肿瘤的文献令人困惑，尤其是关于皮脂腺上皮瘤的概念，一些观察者将其视为一种特定的肿瘤，但另一些人将其定义为具有皮脂腺分化的基底细胞癌，还有一些人将其定义为以未分化基底样细胞为主的皮脂腺腺瘤。通过我们对该谱系内19例良性皮脂腺肿瘤的研究以及对文献的批判性回顾，我们得出以下结论：(a)“皮脂腺上皮瘤”是一个无用的术语；(b)“具有皮脂腺分化的基底细胞癌”这一术语仅应用于具有皮脂腺分化组织学证据的其他常规基底细胞癌；(c)Troy和Ackerman所描述的“皮脂腺腺瘤”代表了具有不同程度皮脂腺分化的良性肿瘤谱系的两端，我们为此提议使用“皮脂腺瘤”这一术语；(d)如此定义的皮脂腺瘤涵盖了具有皮脂腺分化的各种良性肿瘤，如具有皮脂腺分化的浅表上皮瘤和以前“无法分类”的皮脂腺肿瘤，这些肿瘤常见于Muir-Torre综合征患者或 Jadassohn皮脂腺痣内。
