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一种小苏打-过氧化物牙膏对术后伤口愈合的影响。

Effect of a baking soda-peroxide dentifrice on post-surgical wound healing.

作者信息

Dentino A R, Ciancio S G, Bessinger M, Mather M A, Cancro L, Fischman S

机构信息

Department of Periodontics, School of Dentistry, Marquette University, Milwaukee, WI 53233, USA.

出版信息

Am J Dent. 1995 Jun;8(3):125-7.

PMID:8599587
Abstract

PURPOSE

To investigate the effect of a baking soda-hydrogen peroxide (0.75%) dentifrice on wound healing, plaque formation, gingival inflammation, patient comfort, probing depth, and clinical attachment level following gingival flap surgery.

MATERIALS AND METHODS

A randomized, double-blind crossover study involving 25 patients requiring bilateral maxillary gingival flap surgery was completed. The effects of twice daily brushing with a baking soda-hydrogen peroxide dentifrice (Mentadent) or a placebo dentifrice (Crest) were observed over a 28-day post-surgical period. Gingival Index (GI), plaque index (PI), probing depth (PD), clinical attachment level (CAL) and gingival bleeding index (BI) were recorded pre-surgically and at day 28 for each surgical sextant. At days 7 and 14, soft tissue appearance/wound healing (STA) was assessed based on color and edema, PIs were determined and patient comfort was ascertained by report.

RESULTS

Post-surgical wound healing was statistically significantly improved at day 7 with the trend continuing to day 14 when Mentadent dentifrice was used as compared to Crest dentifrice. However, there was no statistical difference in the PI values between the test and control dentifrice throughout the study. Use of Mentadent may be an effective aid in the early phase of healing following gingival flap surgery.

摘要

目的

研究小苏打-过氧化氢(0.75%)牙膏对牙龈瓣手术后伤口愈合、菌斑形成、牙龈炎症、患者舒适度、探诊深度及临床附着水平的影响。

材料与方法

完成一项随机、双盲交叉研究,纳入25例需要双侧上颌牙龈瓣手术的患者。在术后28天观察每天两次使用小苏打-过氧化氢牙膏(门泰登牙膏)或安慰剂牙膏(佳洁士牙膏)刷牙的效果。术前及术后第28天记录每个手术象限的牙龈指数(GI)、菌斑指数(PI)、探诊深度(PD)、临床附着水平(CAL)和牙龈出血指数(BI)。在第7天和第14天,根据颜色和水肿情况评估软组织外观/伤口愈合(STA),确定菌斑指数,并通过患者报告确定患者舒适度。

结果

与佳洁士牙膏相比,使用门泰登牙膏时,术后第7天伤口愈合在统计学上有显著改善,且该趋势持续至第14天。然而,在整个研究过程中,试验牙膏和对照牙膏的菌斑指数值没有统计学差异。使用门泰登牙膏可能有助于牙龈瓣手术后愈合的早期阶段。

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