Pameijer C H, Stanley H R
University of Connecticut, School of Dental Medicine, Department of Prosthodontics, Farmington, CT 06030, USA.
Am J Dent. 1995 Jun;8(3):140-4.
To determine the pulpal biocompatibility of Prisma Universal Bond 2 (PUB-2).
Class V preparations were made in eight subhuman monkeys to approximately 1 mm from the pulp. In Group 1, the enamel was etched, the primer was placed and dried, PUB 2 was painted, and Prisma-Fil inserted. In Goup 2, the cavity floor was covered with visible light-cured Dycal followed by the steps as in group 1. In Group 3, IRM was used as a negative control. In Group 4, MQ55 silicate cement was used as a positive control. The animals were sacrificed at 5, 25, and 60 days and the teeth processed for histological evaluation.
After 5 days, a mild reaction of little concern, which had dissipated in the 25- and 6-day groups, was observed. The material compared favorably to the negative control.