不明原因视神经病变患者的磁共振成像

Magnetic resonance imaging in patients with unexplained optic neuropathy.

作者信息

Golnik K C, Hund P W, Stroman G A, Stewart W C

机构信息

Storm Eye Institute, Medical University of South Carolina, Charleston, USA.

出版信息

Ophthalmology. 1996 Mar;103(3):515-20. doi: 10.1016/s0161-6420(96)30664-7.

DOI:10.1016/s0161-6420(96)30664-7

PMID:8600430

Abstract

PURPOSE

To investigate the anatomic relation between the optic nerve and the adjacent intracranial internal carotid artery (ICA) in patients with unexplained optic neuropathy.

METHODS

Coronal magnetic resonance images (MRIs) of 20 patients with unexplained optic neuropathy and 20 age-matched controls were evaluated with digitizing software.

RESULTS

The distance between the optic nerve and ICA was significantly less on the side ipsilateral to the atrophic optic nerve than either the study group's contralateral optic nerve-ICA distance (P<0.001) or the control group's optic nerve-ICA distance (P<0.001). The diameter of the atrophic optic nerves was significantly less than either the diameter of the study group's contralateral normal nerves (P=0.008) or the control group's nerves (P<0.001). There was no significant difference between the diameters of the ICA flow voids adjacent to the atrophic optic nerves versus either the study group's contralateral ICA flow voids (P=0.91) or the control group's ICA flow voids (P=0.74).

CONCLUSIONS

The authors speculate that the intimate relation between the optic nerve and adjacent ICA may be important in the development of unexplained optic neuropathy. The ICA need not appear abnormal in MRIs.

摘要

目的

研究不明原因视神经病变患者视神经与相邻颅内颈内动脉（ICA）之间的解剖关系。

方法

使用数字化软件对20例不明原因视神经病变患者和20例年龄匹配的对照者的冠状位磁共振成像（MRI）进行评估。

结果

萎缩性视神经同侧视神经与ICA之间的距离显著小于研究组对侧视神经-ICA距离（P<0.001）或对照组视神经-ICA距离（P<0.001）。萎缩性视神经的直径显著小于研究组对侧正常神经的直径（P=0.008）或对照组神经的直径（P<0.001）。与萎缩性视神经相邻的ICA血流空洞直径与研究组对侧ICA血流空洞直径（P=0.91）或对照组ICA血流空洞直径（P=0.74）之间无显著差异。