Subcutaneous Castleman's disease of the wrist.

Castleman's disease usually occurs as a solitary lesion in the mediastinum and less frequently in the neck region. Two variants are recognized, the more common hyaline-vascular type and the plasma cell type. A third hybrid, or intermediate, variant exists that shares features with both the hyaline-vascular and plasma cell types. Uncommonly, these lesions occur outside the mediastinum or neck region. We report a case of subcutaneous Castleman's disease of the intermediate type on the wrist of a 56-year-old woman without systemic symptoms.