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促肾上腺皮质激素原（POMC）和促肾上腺皮质激素释放激素受体（CRH-R）基因在小鼠皮肤中的表达。

The expression of proopiomelanocortin (POMC) and of corticotropin releasing hormone receptor (CRH-R) genes in mouse skin.

作者信息

Slominski A, Ermak G, Hwang J, Mazurkiewicz J, Corliss D, Eastman A

机构信息

Department of Pathology and Laboratory Medicine, Albany Medical College, NY, 12208, USA.

出版信息

Biochim Biophys Acta. 1996 Mar 15;1289(2):247-51. doi: 10.1016/0304-4165(95)00159-x.

DOI:10.1016/0304-4165(95)00159-x
PMID:8600981
Abstract

The proopiomelanocortin (POMC) and the corticotropin releasing hormone receptor (CRH-R) genes are expressed in the skin of the C57BL/6 mouse throughout the entire hair cycle, and CRH immunoreactivity is present in the pilosebaceous unit of the hair follicle and the epidermis. These findings suggest that some components of hypothalamo-pituitary axis are operating in mouse skin.

摘要

促肾上腺皮质激素原（POMC）和促肾上腺皮质激素释放激素受体（CRH-R）基因在C57BL/6小鼠皮肤的整个毛发周期中均有表达，且毛囊和表皮的皮脂腺单位中存在CRH免疫反应性。这些发现表明下丘脑-垂体轴的某些成分在小鼠皮肤中发挥作用。

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